Molecular actions of pentobarbitone on sodium channels in lipid bilayers: role of channel structure
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چکیده
منابع مشابه
the role of thematic structure in comprehending spoken language
in fact this study is concerned with the relationship between the variation in thematice structure and the comprehension of spoken language. so the study focused on the following questions: 1. is there any relationship between thematic structure and the comprehension of spoken language? 2. which of the themes would have greated thematic force and be easier for the subjects to comprehend? accord...
15 صفحه اولSodium channels in planar lipid bilayers. Channel gating kinetics of purified sodium channels modified by batrachotoxin
Single channel currents of sodium channels purified from rat brain and reconstituted into planar lipid bilayers were recorded. The kinetics of channel gating were investigated in the presence of batrachotoxin to eliminate inactivation and an analysis was conducted on membranes with a single active channel at any given time. Channel opening is favored by depolarization and is strongly voltage de...
متن کاملSodium Channels in Planar Lipid Bilayers
Single channel currents of sodium channels purified from rat brain and reconstituted into planar lipid bilayers were recorded . The kinetics of channel gating were investigated in the presence of batrachotoxin to eliminate inactivation and an analysis was conducted on membranes with a single active channel at any given time . Channel opening is favored by depolarization and is strongly voltage ...
متن کاملBatrachotoxin-modified sodium channels in planar lipid bilayers. Characterization of saxitoxin- and tetrodotoxin-induced channel closures
The guanidinium toxin-induced inhibition of the current through voltage-dependent sodium channels was examined for batrachotoxin-modified channels incorporated into planar lipid bilayers that carry no net charge. To ascertain whether a net negative charge exists in the vicinity of the toxin-binding site, we studied the channel closures induced by tetrodotoxin (TTX) and saxitoxin (STX) over a wi...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1994
ISSN: 0007-0912
DOI: 10.1093/bja/72.6.668